Sildalist is a combination drug that typically contains two active ingredients: sildenafil citrate (similar to Viagra) and tadalafil (similar to Cialis). Both sildenafil and tadalafil are phosphodiesterase type 5 (PDE5) inhibitors used to treat erectile dysfunction (ED) by increasing blood flow to the penis, helping men achieve and maintain erections during sexual stimulation. Sildalist, like other ED medications, may continue to be effective over the long term if it is taken as prescribed and continues to address the underlying causes of your ED. Some individuals may develop a tolerance to the medication over time, meaning that the same dose might become less effective. In such cases, a healthcare provider might adjust the dosage or consider alternative treatments. Long-term use of Sildalist can potentially lead to the same side effects that are associated with short-term use. Common side effects include headache, flushing, indigestion, nasal congestion, and changes in vision. It's important to note that side effects can vary from person to person. It's important to emphasize that the information provided here is general in nature. If you're considering using Sildalist or any ED medication on a long-term basis, I strongly recommend discussing your situation with a qualified healthcare provider. They can provide personalized advice based on your medical history, current health status, and any potential risks or benefits associated with long-term use.